USMLE Step 2 CK Practice Bank

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A 16-year-old boy presents to the emergency department with a 3-day history of worsening sore throat, fever, and difficulty swallowing. He has a muffled voice and physical examination reveals a deviated uvula to the left and trismus. Which of the following is the most appropriate next step in management?
  1. Intravenous antibiotics only
  2. Needle aspiration
  3. Computed tomography of the neck
  4. Rapid streptococcal antigen test
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Correct Answer: B (Needle aspiration)

This patient's presentation of fever, severe sore throat, trismus, muffled "hot potato" voice, and uvular deviation is classic for a peritonsillar abscess. The most appropriate next step in management is drainage via needle aspiration or incision and drainage, along with empiric antibiotic therapy.